Table 5 Comparison of the prediction results for different PSSM-based feature description methods on Dataset2 (\(\%\)).

From: Hybrid framework for membrane protein type prediction based on the PSSM

Specific type

Index

Dpc-PSSM

Eedp-PSSM

DF-PSSM

Kse-PSSM

Ab-PSSM

Rpm-PSSM

TG-PSSM

ICNN

Type I

Se

90.20

87.76

70.20

82.04

86.53

82.86

84.08

91.84

Sp

95.56

95.74

92.05

97.05

96.25

96.01

97.20

98.21

ACC

95.20

95.20

90.57

96.03

95.59

95.12

96.31

97.78

Mcc

71.13

70.27

47.91

72.07

71.47

68.19

74.06

83.99

Type II

Se

59.49

50.63

8.86

51.90

54.43

46.84

59.49

67.09

Sp

97.59

97.99

99.69

97.73

97.67

97.56

98.64

98.70

ACC

96.75

96.95

97.70

96.73

96.73

96.45

97.78

98.00

Mcc

44.50

41.20

17.76

40.34

41.69

35.80

53.13

58.93

Type III

Se

11.11

0.00

0.00

0.00

0.00

22.22

0.00

11.11

Sp

99.89

99.94

100

99.94

100

99.94

99.97

99.94

ACC

99.67

99.69

99.75

99.69

99.75

99.75

99.72

99.72

Mcc

14.75

– 0.12

0.00

-0.12

0.00

33.23

– 0.08

19.13

Type IV

Se

64.71

41.18

0.00

29.41

41.18

23.53

41.18

47.06

Sp

99.78

99.94

99.97

99.97

99.89

99.97

99.97

99.94

ACC

99.61

99.67

99.50

99.64

99.61

99.61

99.69

99.69

Mcc

61.01

56.45

11.00

49.38

51.01

43.26

59.91

61.22

Mutipass

Se

91.00

90.15

86.28

92.53

89.99

90.80

92.45

94.92

Sp

96.63

95.65

86.59

95.47

95.56

94.76

96.54

97.69

ACC

92.76

91.87

86.38

93.45

91.73

92.04

93.73

95.78

Mcc

84.42

82.53

70.16

85.54

82.25

82.65

86.28

90.60

Lipid-chain -anchored

Se

27.78

16.67

5.56

22.22

13.89

13.89

22.22

50.00

Sp

99.16

99.58

99.97

99.78

99.66

99.44

99.69

99.24

ACC

98.45

98.75

99.03

99.00

98.81

98.58

98.92

98.75

Mcc

25.57

21.23

19.06

32.90

19.67

15.97

30.09

44.10

GPI-anchored

Se

51.22

60.98

12.20

48.78

63.41

43.90

53.66

82.93

Sp

99.69

99.55

99.92

99.49

99.75

99.75

99.75

99.80

ACC

99.14

99.11

98.92

98.92

99.33

99.11

99.22

99.61

Mcc

57.55

60.53

27.29

50.12

68.30

53.68

61.33

82.73

Peripheral

Se

81.55

85.55

71.96

85.55

84.41

80.40

89.41

88.84

Sp

95.08

93.77

88.19

93.84

92.84

92.70

93.29

95.80

ACC

92.45

92.18

85.04

92.23

91.20

90.32

92.54

94.45

Mcc

76.05

76.19

56.12

76.33

73.56

70.39

78.00

82.73

ALL

OA

87.01

86.71

78.44

87.84

86.38

85.48

88.96

90.51

Dimension

400-D

400-D

20-D

400-D

400-D

400-D

8000-D

–