Table 3 Analysis of risk factors of overall survival.

From: Prognostic impact of pulmonary dysfunction in older gastric cancer patients

Variables

Group

n

5-year OS (%)

Univariate

Multivariate

p value

HR

95% CI

p value

Sex

Male

267

69.7

0.137

   

Female

85

78.9

    

BMI

 < 22

146

63.2

0.005*

1.41

0.44–1.10

0.129

 ≥ 22

206

78.3

    

CCI

 ≥ 1

197

67.5

0.007*

1.58

1.01–2.51

0.044*

0

155

77.2

    

Smoking history

Presence

182

70.2

0.873

   

Absence

170

73.8

    

History of pulmonary disease

Presence

23

56.9

0.042*

1.27

0.63–2.81

0.517

Absence

329

73.1

    

%VC

 < 80%

26

37.2

 < 0.001*

2.08

1.03–3.88

0.041*

 ≥ 80%

326

74.4

    

FEV1.0%

 ≥ 70%

229

70.9

0.568

   

 < 70%

123

73.9

    

Surgical procedure

PG/TG

DG/PPG

133

68.3

0.322

   
 

219

74.1

    

Surgical approach

Laparotomy

152

63.5

 < 0.001*

1.21

0.74–1.96

0.444

Laparoscopy

200

78.1

    

Postoperative complications a

Presence

69

64.2

0.064

1.05

0.59–1.98

0.874

Absence

283

73.8

    

Postoperative pneumonia a

Presence

15

30.7

 < 0.001*

5.53

2.13–13.51

 < 0.001*

Absence

337

73.5

    

Stage

III

96

47.4

 < 0.001*

3.44

2.12–5.60

 < 0.001*

I/II

256

80.7

    

Adjuvant chemotherapy

Presence

71

68.9

0.385

   

Absence

281

72.9

    
  1. %VC, vital capacity percentage; BMI, body mass index; CCI, Charlson comorbidity score; CI, confidence interval; DG, distal gastrectomy; FEV1.0%, percent expiratory volume in one second; HR, hazard ratio; OS, overall survival; PG, proximal gastrectomy; PPG, pylorus preserving gastrectomy; TG, total gastrectomy.
  2. *Indicates significant difference (p < 0.05).
  3. aClavien-Dindo classification Grade II or more.
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