Table 3 Oncological features of patients with ESRD and UTUC.

	Unilateral RNU (N = 413)		Sequential unilateral RNU (N = 99)		Bilateral RNU (N = 64)		p-value
	n	%	n	%	n	%	p-value
Tumor location
Not available	2	0.5	0	0.0	0	0.0	0.002**
Renal pelvis	159	38.5	28	28.3	11	17.2
Ureter	148	35.8	38	38.4	22	34.4
Renal pelvis and ureter	104	25.2	33	33.3	31	48.4
Multicentric
Not available	8	1.9	2	2.0	3	4.7	< 0.001**
No	208	50.4	46	46.5	9	14.1
Yes	197	47.7	51	51.5	52	81.3
Tumor size
Not available	27	6.5	7	7.1	10	15.6	0.044*
< 1 cm	43	10.4	15	15.2	13	20.3
≥ 1 & < 2 cm	106	25.7	27	27.3	17	26.6
≥ 2 & < 3 cm	75	18.2	16	16.2	9	14.1
≥ 3 cm	162	39.2	34	34.3	15	23.4
Tumor grade
Low grade	42	10.2	10	10.2	3	4.8	0.692
High grade	343	83.7	85	86.7	55	87.3
Grade x	8	2.0	1	1.0	2	3.2
Grade 2	17	4.1	2	2.0	3	4.8
Pathological T stage
pTis	20	4.9	5	5.1	6	9.4	0.794
pTa	75	18.2	18	18.2	13	20.3
pT1	127	30.8	27	27.3	18	28.1
pT2	71	17.2	23	23.2	11	17.2
pT3	103	25.0	24	24.2	14	21.9
pT4	15	3.6	1	1.0	2	3.1
pT0	1	0.2	1	1.0	0	0.0
Pathological N stage
pN0	111	26.9	26	26.3	21	32.8	0.376
pN1	6	1.5	0	0.0	0	0.0
pN2	6	1.5	0	0.0	2	3.1
pNx	290	70.2	73	73.7	41	64.1
Bladder UC
No	227	55.0	30	30.3	18	28.1	< 0.001**
Past history of bladder UC	55	13.3	35	35.4	10	15.6
Concurrent bladder UC	121	29.3	34	34.3	35	54.7
Not available	10	2.4	0	0.0	1	1.6
Carcinoma in situ
No	298	72.5	68	68.7	35	55.6	0.023*
Yes	113	27.5	31	31.3	28	44.4
Lymphovascular invasion
No	350	85.6	89	89.9	52	82.5	0.380
Yes	59	14.4	10	10.1	11

ESRD end stage renal disease, N node, T tumor, UC urothelial carcinoma, UTUC upper tract urothelial carcinoma, x unable to assess.
*p < 0.05, **p < 0.005.

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