Table 1 Baseline characteristics of 190 participants with tSCI stratified by AIS grade at discharge in the observational study.

From: Association of systemic inflammatory response index and clinical outcome in acute traumatic spinal cord injury patients

 

Overall

(N = 190)

Good outcome (AIS D to E)

(N = 111)

Poor outcome (AIS A to C)

(N = 79)

P value

Male, n (%)

133(70.00)

71(63.96)

62(78.48)

0.037

Age (year, mean ± SD)

53 ± 13

52 ± 13

55 ± 13

0.076

MAP (mmHg, mean ± SD)

93 ± 14

97 ± 13

88 ± 15

 < 0.001

TC (mmol/L, median (IQR))

4.45 [3.74, 4.95]

4.57 [3.97, 5.06]

3.96 [3.47, 4.53]

0.001

ALT (U/L, median (IQR))

23 [18, 39]

22 [16, 31]

31 [18, 44]

0.004

Scr (μmol/L, median (IQR))

69.00 [58.95, 81.50]

67.00 [59.00, 79.00]

71.20 [59.12, 84.53]

0.197

TP (g/L, median (IQR))

61.65 [56.95, 67.20]

64.80 [59.70, 68.90]

58.30 [54.95, 61.65]

 < 0.001

HGB (g/L, mean ± SD)

126 ± 19

131 ± 17

120 ± 20

 < 0.001

WBC (× 109/L, mean ± SD)

9.63 ± 3.10

9.11 ± 2.74

10.35 ± 3.43

0.006

ANC (× 109/L, median (IQR))

7.58 [5.65, 9.72]

6.96 [5.14, 9.04]

8.72 [6.76, 10.22]

0.001

LY (× 109/L, median (IQR))

1.01 [0.66, 1.47]

1.23 [0.78, 1.60]

0.76 [0.52, 1.09]

 < 0.001

MONO (× 109/L, median (IQR))

0.44 [0.18, 0.62]

0.44 [0.17, 0.60]

0.41 [0.18, 0.69]

0.658

PLT (× 109/L, mean ± SD)

209.34 ± 68.99

223.79 ± 67.01

189.03 ± 66.98

0.001

NLR (median (IQR))

7.57 [4.33, 13.70]

5.65 [3.71, 10.88]

11.80 [6.30, 17.94]

 < 0.001

SIRI (median (IQR))

2.58 [1.39, 4.10]

1.99 [1.16, 3.13]

3.87 [2.24, 6.93]

 < 0.001

Spinal surgery, n (%)

150 (78.95)

83 (74.77)

67 (84.81)

0.107

Mechanism of injury, n (%)

0.061

 Motor vehicle accident

24 (12.63)

19 (17.12)

5 (6.33)

 

 High fall

33 (17.37)

14 (12.61)

19 (24.05)

 

 Stumble

79 (41.58)

47 (42.34)

32 (40.51)

 

 Blow to spine

46 (24.21)

25 (22.52)

21 (26.58)

 

 Others

8 (4.21)

6 (5.41)

2 (2.53)

 

Level of cord injury, n (%)

0.034

 Cervical

148 (77.89)

90 (81.08)

58 (73.42)

 

 Thoracic

15 (7.89)

4 (3.60)

11 (13.92)

 

 Lumbar

18 (9.47)

13 (11.71)

5 (6.33)

 

 Others

9 (4.74)

4 (3.60)

5 (6.33)

 

AIS grade at admission, n (%)

 < 0.001

 A

40 (21.05)

3 (2.70)

37 (46.84)

 

 B

24 (12.63)

5 (4.50)

19 (24.05)

 

 C

41 (21.58)

18 (16.22)

23 (29.11)

 

 D

85 (44.74)

85 (76.58)

0 (0.00)

 
  1. tSCI, traumatic spinal cord injury; AIS, association impairment scale; MAP, mean arterial pressure; TC, total cholesterol; ALT, alanine aminotransferase; Scr, serum creatinine; TP, total protein; HGB, hemoglobin; WBC, white blood cell; ANC, absolute neutrophil count; LY, lymphocyte count; MONO, mono cell count; PLT, platelet; NLR, neutrophil-to-lymphocyte ratio; SIRI, systemic inflammatory response index.
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