Figure 4 | Scientific Reports

Figure 4

From: Neural mechanisms responsible for vagus nerve stimulation-dependent enhancement of somatosensory recovery

Figure 4

Blocking plasticity prevents VNS-dependent enhancement of somatosensory recovery. VNS paired with tactile rehabilitation significantly improves recovery of forelimb somatosensation in control rats (ACh+; VNS, n = 4). Depletion of forebrain acetylcholine, which blocks cortical plasticity, significantly impairs VNS-dependent recovery (ACh−; VNS, n = 6). **Indicates p < 0.001 across groups. Data are presented as mean ± SEM.

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