Figure. 1

illustrates an eye with type II MNV. Images (a–c) were captured at baseline, while images (d–f) were obtained at week 4 and images (g–i) at week 8. Spectral domain optical coherence tomography (SD-OCT) B-scans (images a, d, g) demonstrate fluid segmentation based on automated deep learning. The red colour indicates the presence of intraretinal fluid (IRF), the green colour indicates the presence of subretinal fluid (SRF), and the blue colour indicates the presence of pigment epithelial detachment (PED). In OCT angiography (OCTA) en face images, the magenta colour represents the size of the macular neovascular membrane (MNV) lesion, which corresponds to the area covered by the entire MNV membrane. The yellow colour represents the vessel area, which is the area covered by the pure flow signal, as shown in images (c, f and i). The corresponding areas in square millimetres are shown in the upper right corner. In the OCTA images, the red lines indicate the position of the corresponding SD-OCT B-scan. The fluid volumes at baseline were as follows: The IRF volume was 431 nl, the SRF volume was 461 nl, and the PED volume was 169 nl. The fluid volumes at week 4 were as follows: IRF volume, 10 nl; SRF volume, 43 nl; PED volume, 174 nl. The fluid amounts at week 8 were as follows: IRF volume, 17 nl; SRF volume, 0 nl; PED volume, 163 nl.