Table 1 presents the median (interquartile range, IQR) amount of fluid (nl) in the different retinal compartments and the median (IQR) values of the MNV membrane parameters at baseline and follow-up.

Descriptive analysis of all study eyes
	IRF in nl (median)	SRFin nl (median)	PED in nl (median)	Lesion size in mm² (median)
Baseline (n = 230)	3.05 (IQR:70.71)	156.64 (IQR: 466.67)	273.94 (IQR: 609.95)	0.28 (IQR: 1.21)
Week 4 (n = 126)	0.07 (IQR: 0.99)	0.49 (IQR: 4.52)	195.46 (IQR: 338.91)	0.85 (IQR: 1.75)
Week 8 (n = 121)	0.04 (IQR: 1.15)	0.12 (IQR: 1.37)	163.64 (IQR: 360.57)	0.64 (IQR: 1.85)
Week 12 (n = 114)	0.07 (IQR: 1.04)	0.16 (IQR: 1.35)	178.40 (IQR: 360.32)	0.67 (IQR: 1.46)
Week 28 (n = 79)	0.11 (IQR: 0.61)	0.5 (IQR: 2.60)	152.54 (IQR: 296.46)	0.16 (IQR: 0.63)
Week 32 (n = 93)	0.03 (IQR: 0.80)	0.83 (IQR: 3.16)	121.86 (IQR: 332.79)	0.17 (IQR: 0.55)
Week 48 (n = 16)	0.01 (IQR: 3.92)	0.04 (IQR: 0.87)	101.04 (IQR: 251.67)	0.23 (IQR: 0.28)
Week 60 (n = 72)	0.06 (IQR: 0.44)	0.30 (IQR: 1.85)	146.71 (IQR: 289.83)	0.27 (IQR: 2.60)
Week 64 (n = 79)	0.06 (IQR: 0.86)	0.55 (IQR: 3.19)	134.66 (IQR: 314.39)	0.21 (IQR: 0.86)

Descriptive analysis of AngioVue OCTA sub cohort
	IRF in nl (median)	SRFin nl (median)	PED in nl (median)	Lesion size in mm² (median)	Vessel area in mm² (median)
Baseline (n = 80)	2.3 (IQR: 59.27)	107.58 (IQR: 394.97)	159.87 (IQR: 512.73)	0.21 (IQR: 0.84)	0.18 (IQR: 0.64)
Week 4 (n = 74)	0.09 (IQR: 0.73)	0.26 (IQR: 3.47)	139.59 (IQR: 317.21)	0.36 (IQR: 1.39)	0.22 (IQR: 0.76)
Week 8 (n = 70)	0.02 (IQR:0.25)	0.07 (IQR: 0.77)	114.51 (IQR: 261.98)	0.54 (IQR: 1.28)	0.31 (IQR: 0.71)
Week 12 (n = 72)	0.06 (IQR: 0.49)	0.10 (IQR: 0.69)	142.05 (IQR: 323.17)	0.67 (IQR: 1.33)	0.39 (IQR: 0.74)

The number of patients (n) at a given timepoint is also provided. The descriptive analysis of the AngioVue OCTA sub-cohort is derived from study subjects of the same study. It should be noted that the number of n varies due to different predefined visits in the studies.

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