Fig. 7
From: Bovine lactoferrin inhibits Plasmodium berghei growth by binding to heme
Exploration of binding sites for C-lobes interacting with heme. (a) Regions on the bLF surface that retain their secondary structure, including fragments resulting from trypsin treatment, are designated as C-1a (red), C-1b (green), C-2 (blue), and hinge (yellow)., On the right, the molecular surface model (front and side) is described; (b) Assessment of the ability to inhibit hemozoin formation of various region derived C-lobe. various samples were tested at 50 µM concentrations. All tests were conducted in triplicate.
