Fig. 4
From: Generation of rat offspring from ovarian oocytes by xenotransplantation

Maturation culture of xenotransplanted oocytes and in vitro fertilized embryos. TCOCs (a) before IVM, and (b) after IVM. (c) Embryos in a pronuclear stage, 5–6 h after IVF; (d) Embryos in a 2-cell stage, 2 days after IVF. (e) Percentage of LCOCs after IVM culture of oocytes collected under three different hormone administration conditions (1–3). (1) PMSG and hCG administered 48 h apart, and oocytes collected 5 h after hCG. 26.70 [17.69, 35.86], n = 4; (2) PMSG administered twice 48 h apart, and oocytes collected 21 h after PMSG. 0.00 [0.00, 9.09], n = 3; (3) PMSG administered twice 48 h apart, and oocytes collected 29 h after PMSG. 0.00 [0.00, 12.77], n = 5, p = 0.07. Data are median and interquartile range and obtained Mann–Whitney U test.