Fig. 4
From: Metformin enhances osteogenic differentiation of BMSC by modulating macrophage M2 polarization
(a) The activity of BMSCs under different macrophage OCM was assessed after 7 days of culture. (b) Relative mRNA expression levels of osteogenic genes OCN, Runx2, ALPand COL-1 in BMSCs cultured with different macrophage OCMs.*P < 0.05, **P < 0.01, ***P < 0.001, and****P < 0.0001.
