Table 1 Baseline characteristics of all study patients.

From: Lymphopenia associated with whole-brain radiotherapy and its effects on clinical outcomes of patients with brain metastases

Characteristic

No. of patients (%)

Age (years)

 < 60

77 (66.4)

 ≥ 60

39 (33.6)

Sex

 Male

60 (51.7)

 Female

56 (48.3)

ECOG score

 0–2

96 (82.8)

 3

20 (17.2)

Primary tumor

 Pulmonary

64 (55.2)

 Extra-pulmonary

52 (44.8)

History of extracranial RT

 Yes

31 (26.7)

 No

85 (73.2)

Numbers of brain metastases

 ≤ 4

77 (55.0)

 > 4

39 (45.0)

Subsequent systemic therapy

 Chemotherapy

53 (45.7)

 Without chemotherapy

63 (54.3)

Chemotherapy

 WBRT

24 (45.3)

 Focal radiotherapy

29 (54.7)

Steroid use

 Yes

51 (44.0)

 No

65 (56.0)

Radiation modality

 WBRT with or without local boost

37 (31.9)

 Focal radiotherapy

79 (68.1)

Per fractionation of WBRT (Gy)

 2.5

11 (29.7)

 3

26 (70.3)

Per fractionation of focal RT (Gy)

 3

44 (55.7)

 4

35 (44.3)

  1. ECOG, Eastern Cooperative Oncology Group; WBRT, whole-brain radiotherapy.