Fig. 1
From: Using weight loss to predict outcome and define a humane endpoint in preclinical sepsis studies
Number of mice used in statistical and power analyses. Experiments were conducted from June 2014 to March 2023. Exclusion criteria included death just following anaesthesia (n = 39) and incorrect injection of the infectious agent (n = 4). Statistical analyses were performed on 2'357 mice. Power analyses were performed on 1858 and 2199 mice for the in-house and simulation-based calculations. Experiments without an appropriate \({H}_{0}\) (n = 271) or determining LD50 (n = 228) were excluded from in-house power analysis.
