Table 1 The characteristics of the DLBCL patients in GEO datasets.

From: A Bruton tyrosine kinase inhibitor-resistance gene signature predicts prognosis and identifies TRIP13 as a potential therapeutic target in diffuse large B-cell lymphoma

Characteristic

Training cohort

GSE31312 (n = 471)

Validation cohort 1

GSE87371 (n = 122)

Validation cohort 2

GSE10846 (n = 233)

Gender

 Male/female

271/200

59/63

134/99

Age (year)

 Mean (range)

61.86 (18–92)

63.36 (20–87)

60.16 (17–92)

 ≥ 60

285 (60.51%)

100 (81.97%)

124 (53.22%)

 < 60

186 (39.49)

22 (18.03%)

109 (46.78%)

(COO) subtypes

 ABC

200 (42.46%)

56 (45.90%)

93 (39.91%)

 GCB

227 (48.20%)

42 (34.43%)

107 (45.92%)

 Other

44 (9.34%)

24 (19.67%)

33 (14.16%)

IPI

 ≥ 2

255 (54.14%)

104 (85.25%)

 < 2

170 (36.09%)

18 (14.75%)

 NA

46 (9.77%)

Stage

 I–II

24 (19.67%)

105 (45.06%)

 III–IV

98 (80.33%)

121 (51.93%)

 NA

7 (3.00%)

  1. COO: cell-of-origin, IPI: International Prognostic Index, ABC: activated B-cell-like, GCB: germinal center B-cell-like, NA: not available.