Scientific Reports

Table 2 Screening of the experimental conditions for the Synthesis of pentaphenylpyrrole.

From: Palladium-immobilized triazine dendrimer on magnetic nanoparticles: as reusable microreactor for solvent-dependent synthesis strategy of 2,3-diphenylindoles and pentaphenylpyrrole derivatives


Entry	Base	Anil: DPA	Pd (mol%)	Solvent	additive	T (°C)	Yield (%)
1	Na₂CO₃	1:2	0.3	Dioxane	–	90	41
2	K₂CO₃	1:2	0.3	Dioxane	–	90	62
3	NaOAc	1:2	0.3	Dioxane	–	90	77
4	NaOAc	1:2	0.3	Dioxane	LiCl	90	72
5	NaOAc	1:2.2	0.3	Dioxane	–	90	73
6	NaOAc	1:2.5	0.3	Dioxane	–	90	75
7	Na₂CO₃	1:2	0.3	H₂O	–	90	24
8	NaOAc	1:2	0.3	THF	–	60	40
9	NaOAc	1:2	0.3	DMSO	–	90	10
10	NaOAc	1:2	0.3	DMF	LiCl	90	15
11	NaOAc	1:2	0.5	Dioxane	–	90	75
12	NaOAc	1:2	0.2	Dioxane	–	90	65
13	NaOAc	1:2	0.3	Dioxane	–	80	58
14	NaOAc	1:2	0.3	Dioxane	–	100	73

^aReaction conditions: aniline (Anil), diphenylacetylene (DPA), base (1 mmol), additive (0.5 mmol), 10 mL solvent and Pd-TDSN for 8 h.
^bIsolated yield.

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