Fig. 4 | Scientific Reports

Fig. 4

From: Proteomics identifies multiple retinitis pigmentosa associated proteins involved in retinal degeneration in a mouse model bearing a Pde6b mutation

Fig. 4

Functional analysis of DEPs in rd10 retinas (n = 3 retinas per group). (A) (B) KEGG pathways enrichment with DEPs (FC > 2, p < 0.05) in rd10 retinas at 5w and 8w compared to age-matched WT retinas50,51,52. (C) BP pathways by DAVID enrichment with DEPs (FC > 2, FDR < 0.25) in rd10 retinas at 5w and 8w. (D) (E) (F) Heatmaps showing proteins associated with top 10 BP pathways enriched in 5w or 8w. FC: fold change; 5w: 5 weeks; 8w: 8 weeks; DEP: differentially expressed protein; BP: biological process; FDR: false discovery rates.

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