Table 5 Predicted epitopes specific to selected MHC-I alleles.
Protein | Allele | Start | End | Peptide | IC50 | Score | Percentile rank | Antigenicity (Threshold 0.4) |
|---|---|---|---|---|---|---|---|---|
gbs2106 | HLA-B*57:01 | 119 | 127 | ATGVPQSTW | 43.05 | 0.986202 | 0.01 | 0.6051 (Antigen) |
HLA-B*58:01 | 119 | 127 | ATGVPQSTW | 21.19 | 0.981843 | 0.01 | ||
HLA-A*31:01 | 125 | 133 | STWEHIIAR | 6.48 | 0.980607 | 0.01 | 0.4145 (Antigen) | |
HLA-A*68:01 | 125 | 133 | STWEHIIAR | 8.52 | 0.979415 | 0.01 | ||
HLA-A*11:01 | 125 | 133 | STWEHIIAR | 18.14 | 0.939904 | 0.01 | ||
HLA-A*33:01 | 125 | 133 | STWEHIIAR | 14.6 | 0.931901 | 0.01 | ||
HLA-A*68:01 | 125 | 133 | STWEHIIAR | 8.52 | 0.979415 | 0.01 | ||
HLA-A*30:01 | 5 | 14 | RVAKKSKMTK | 26.35 | 0.851112 | 0.01 | 0.7582 (Antigen) | |
HLA-A*30:01 | 3 | 11 | KVRVAKKSK | 8.81 | 0.833475 | 0.01 | 0.5989 (Antigen) | |
HLA-B*58:01 | 118 | 127 | AATGVPQSTW | 17.9 | 0.970257 | 0.02 | 0.5503 (Antigen) | |
HLA-A*30:01 | 6 | 14 | VAKKSKMTK | 25.18 | 0.822865 | 0.02 | 0.6103 (Antigen) | |
HLA-A*30:01 | 12 | 20 | MTKATSKSK | 7.79 | 0.810638 | 0.02 | 0.8605 (Antigen) | |
HLA-A*30:02 | 72 | 80 | ATSQAQQAY | 99.93 | 0.804837 | 0.02 | 0.8969 (Antigen) | |
HLA-A*02:06 | 114 | 122 | AQMAAATGV | 3.79 | 0.756267 | 0.09 | 0.6632 (Antigen) | |
HLA-A*68:01 | 166 | 175 | QVNSAIKAYR | 8.29 | 0.853737 | 0.15 | 0.4805 (Antigen) | |
HLA-A*68:01 | 80 | 88 | YAVTETTYR | 8.8 | 0.871343 | 0.12 | 0.4951 (Antigen) | |
HLA-A*02:03 | 114 | 122 | AQMAAATGV | 7.84 | 0.448592 | 0.29 | 0.6632 (Antigen) | |
SIP | HLA-A*24:02 | 361 | 369 | SYVIWQQKF | 12.52 | 0.981696 | 0.01 | 0.1718 (Non-antigen) |
HLA-A*23:01 | 361 | 369 | SYVIWQQKF | 9.82 | 0.980705 | 0.01 | ||
HLA-A*03:01 | 132 | 141 | KTYSSAPALK | 6.22 | 0.981161 | 0.01 | 0.7138 (Antigen) | |
HLA-A*11:01 | 132 | 141 | KTYSSAPALK | 9.48 | 0.92828 | 0.01 | ||
HLA-A*30:01 | 132 | 141 | KTYSSAPALK | 5.32 | 0.814906 | 0.02 | ||
HLA-B*35:01 | 60 | 69 | YPETTLTVTY | 6.72 | 0.977324 | 0.01 | 0.4352 (Antigen) | |
HLA-A*24:02 | 396 | 404 | HYDHVHVSF | 89.47 | 0.970255 | 0.01 | 0.5357 (Antigen) | |
HLA-A*23:01 | 396 | 404 | HYDHVHVSF | 91.95 | 0.952329 | 0.01 | ||
HLA-A*11:01 | 221 | 229 | ASAKVVTPK | 6.32 | 0.969446 | 0.01 | 0.8060 (Antigen) | |
HLA-A*68:02 | 201 | 209 | ETPAPVAKV | 9.76 | 0.965194 | 0.01 | 0.2726 (Non-antigen) | |
HLA-B*15:01 | 295 | 303 | GLQPHVAAY | 29.52 | 0.960247 | 0.01 | 1.4739 (Antigen) | |
HLA-A*32:01 | 375 | 383 | SIYGPANTW | 5032.22 | 0.928183 | 0.01 | −0.0515 (Non antigen) | |
HLA-A*11:01 | 135 | 143 | SSAPALKSK | 28.04 | 0.923021 | 0.01 | 0.9290 (Antigen) | |
HLA-A*26:01 | 126 | 134 | TIVSPMKTY | 138.3 | 0.920484 | 0.02 | −0.3823 (Non-antigen) | |
HLA-A*68:02 | 38 | 46 | EAMSIDMNV | 4.23 | 0.904474 | 0.02 | 1.7968 (Antigen) | |
HLA-A*30:01 | 72 | 80 | KSHTATSMK | 5.32 | 0.872354 | 0.01 | 1.1728 (Antigen) | |
HLA-A*32:01 | 132 | 140 | KTYSSAPAL | 27 | 0.783714 | 0.02 | 0.4013 (Antigen) | |
HLA-A*68:02 | 355 | 363 | MAANNISYV | 3.41 | 0.769352 | 0.06 | −0.0200 (Non-antigen) | |
HLA-A*02:06 | 355 | 363 | MAANNISYV | 7.27 | 0.509716 | 0.24 | ||
HLA-A*02:03 | 355 | 363 | MAANNISYV | 7.34 | 0.339212 | 0.43 | ||
HLA-A*68:02 | 4 | 12 | WTARTVSEV | 6.46 | 0.65616 | 0.1 | −0.1547 (Non-antigen) | |
HLA-A*68:01 | 311 | 320 | YGVNEFSTYR | 6.78 | 0.850086 | 0.15 | −0.0181 (Non-antigen) | |
HLA-A*68:02 | 238 | 246 | HVSAPAVPV | 6.92 | 0.863818 | 0.03 | 0.6745 (Antigen) | |
HLA-A*68:01 | 40 | 49 | MSIDMNVLAK | 7.6 | 0.707093 | 0.31 | 1.3531 (Antigen) | |
HLA-A*02:03 | 354 | 363 | NMAANNISYV | 8.36 | 0.161842 | 0.98 | 0.2654 (Non-antigen) | |
HLA-A*68:02 | 201 | 209 | ETPAPVAKV | 9.76 | 0.965194 | 0.01 | 0.2726 (Non-antigen) | |
HLA-B*07:02 | 217 | 225 | APRVASAKV | 9.86 | 0.957802 | 0.03 | 1.2344 (Antigen) |
