Fig. 3
From: On the utility of cerebrospinal fluid biomarkers in canine neurological disorders

Sensitivity and specificity of Aβ1-42, NfL, NSE and total tau biomarkers for the differentiation between diagnostic groups. Sensitivity and specificity of biomarkers to distinguish between the control group with Idiopathic Epilepsy (controls) and individual diagnoses (MUO, tumors, CM/SM/M) (A–C), among diagnoses (D–F), and individual diagnoses vs. the other two (G–I) is shown. MUO = Meningoencephalitis of Unknown Origin; CM/SM/M, Chiari malformation = CM, Syringomyelia = SM, Myelitis = M; sensitivity = optimal sensitivity (TPF); specificity = optimal specificity (1 − FPF).