Table 1 Box–Behnken design for optimizing factors in degradation of AT and ME using ZnO NPs/Zeolite and TiO₂NPs/zeolite as the catalysts.

Factor	Name	Units	Type	Minimum	Maximum	Mean	Std. Dev
A	Drug concentration	mg L^-1	Numeric	15.00	45.00	30.00	9.82
B	pH	–	Numeric	3.00	7.00	5.00	1.31
C	Catalyst amount	mg	Numeric	200.00	500.00	350.00	98.20
D	H₂O₂ concentration	mM	Numeric	1.0000	3.00	2.00	0.6547

Std	Run	A	B	C	D	ZnO NPs/Zeolite		TiO₂ NPs/Zeolite
Std	Run	A	B	C	D	R% For AT	R% for ME	R% for AT	R% for ME
24	1	0	1	0	1	81.77	83.59	79.59	82.52
25	2	0	0	0	0	96.45	92.45	91.36	95.07
14	3	0	1	−1	0	67.87	67.69	64.69	62.62
27	4	0	0	0	0	93.19	95.45	93.36	91.85
5	5	0	0	−1	−1	74.13	74.95	74.95	72.88
13	6	0	−1	−1	0	77.61	79.43	80.43	84.36
21	7	0	−1	0	−1	77.49	79.31	77.31	80.24
10	8	1	0	0	−1	78.66	78.48	79.48	78.41
20	9	1	0	1	0	91.14	92.96	85.96	83.89
16	10	0	1	1	0	84.49	86.31	81.31	87.24
22	11	0	1	0	−1	70.59	70.41	66.41	67.34
28	12	0	0	0	0	95.63	91.32	95.97	94.56
26	13	0	0	0	0	91.79	94.79	92.13	90.45
29	14	0	0	0	0	94.06	90.83	96.77	92.24
12	15	1	0	0	1	89.84	88.66	89.66	87.59
18	16	1	0	−1	0	77.36	77.18	80.18	78.11
9	17	−1	0	0	−1	69.42	71.24	64.24	69.17
7	18	0	0	−1	1	71.35	72.17	70.17	74.1
3	19	−1	1	0	0	70.02	70.84	60.84	66.77
2	20	1	−1	0	0	86.16	86.98	86.98	88.91
1	21	−1	−1	0	0	80.31	84.82	80.82	86.75
15	22	0	−1	1	0	88.55	89.37	87.37	91.3
6	23	0	0	1	−1	73.95	74.77	68.77	74.7
11	24	−1	0	0	1	80.6	84.42	77.42	84.35
23	25	0	−1	0	1	88.67	92.49	90.49	95.42
19	26	−1	0	1	0	81.9	85.72	76.72	84.65
8	27	0	0	1	1	89.09	94.91	89.91	93.84
4	28	1	1	0	0	82.34	83.16	85.16	83.09
17	29	−1	0	−1	0	68.12	69.94	64.94	68.87

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