Table 3 Mixed-effects multivariable regression models of BSID-II’s Mental and Psychomotor Development Indices in the early life exposures in Mexico to ENvironmental Toxicants (ELEMENT) cohort.
Variables | Mental | Psychomotor | ||||
|---|---|---|---|---|---|---|
β | 95% CI | p-value | β | 95% CI | p-value | |
C-Sect. (0 = vaginal, 1 = cesarean section) | -0.39 | (-1.20, 0.42) | 0.347 | -0.49 | (-1.26, 0.28) | 0.211 |
Prematurity (0 = 37 weeks or more, 1 = less than 37 weeks) | -1.67 | (-3.13, -0.21) | 0.025 | -2.01 | (-3.40, -0.61) | 0.005 |
Mother schooling (years) | 0.31 | (0.05, − 0.11) | < 0.001 | 0.11 | (-0.03, 0.25) | 0.122 |
Mother’s IQ (WAISa) | 0.08 | (-0.02, − 0.12) | < 0.001 | 0.05 | (0.02, 0.08) | 0.001 |
Mother’s age (years) | 0.05 | (0.05, − 0.11) | 0.166 | 0.03 | (-0.03, 0.10) | 0.305 |
Child’s sex (0 = girls, 1 = boys) | -1.81 | (-2.51, -1.10) | < 0.001 | -1.54 | (-2.21, -0.87) | < 0.001 |
Mother’s Marital status (0 = coupled, 1 = single) | -0.15 | (-0.79, 0.50) | 0.661 | -0.78 | (-1.40, -0.17) | 0.012 |
Child’s age in months (3rd degree polynomial) b | ||||||
Age | 0.80 | (0.59–1.01) | < 0.001 | 0.87 | (0.64, 1.11) | < 0.001 |
Age2 | -0.07 | (-0.08, -0.06) | < 0.001 | -0.04 | (-0.05, -0.02) | < 0.001 |
Age3 | 1 × 10−3 | (1 × 10−3, 1 × 10−3) | < 0.001 | 1 × 10−3 | (1 × 10−3,1 × 10−3) | < 0.001 |
Calendar date of assessment (days) | -1 × 10−3 | (-1 × 10−3, -1 × 10−3) | < 0.001 | -1 × 10−3 | (-1 × 10−3, -1 × 10−3) | < 0.001 |
Constant | 99.7 | (94.4, 104.9) | < 0.001 | 96.407 | (91.3, 101.5) | < 0.001 |
Observations | 7158 | 7146 | ||||
Number of children | 1402 | 1402 | ||||