Table 2 Toxicity of the pyrrolone derivatives against field strain of third larval instar of Culex pipiens after 72 h of exposure.

From: Rational design and synthesis of new pyrrolone candidates as prospective insecticidal agents against Culex pipiens L. Larvae

Compd. (µg/mL)

LC25 (aF.l. at 95%)

LC50 (aF.l. at 95%)

LC90 (aF.l. at 95%)

bSlope ± SE

cX2

P

Relative potency

2

3.63

(1.94–5.58)

18.37

(13.57–23.83)

400.54

(241.39–841.78)

0.95 ± 0.11

4.38

0.35

4.17

3

8.29

(5.25–11.57)

40.46

(31.53–52.62)

822.36

(459.46–1935.58)

0.97 ± 0.10

0.77

0.94

1.89

4

5.15

(2.98–7.58)

25.65

(19.58–32.99)

541.13

(316.77–1186.20)

0.96 ± 0.11

2.49

0.64

2.99

5

4.33

(2.41–6.53)

21.94

(16.50–28.32)

478.20

(282.56–1035.81)

0.95 ± 0.11

2.36

0.66

3.49

6

5.96

(3.54–8.64)

29.84

(22.96–38.48)

636.19

(364.61–442.60)

0.96 ± 0.10

2.08

0.72

2.56

7

10.07

(6.71–13.65)

45.61

(35.93–59.05)

804.04

(460.93–1801.31)

1.02 ± 0.13

1.39

0.84

1.67

8

6.97

(4.29–9.90)

34.10

(26.48–44.01)

695.70

(397.02–1583.31)

0.97 ± 0.11

1.75

0.78

2.24

9

2.74

(1.50–4.19)

11.52

(8.35–14.91)

175.71

(119.97–299.55)

1.08 ± 0.10

8.13

0.08

6.65

10

2.90

(1.58–4.45)

12.68

(9.23–16.41)

208.34

(139.04–368.70)

1.05 ± 0.16

6.74

0.15

6.04

11

15.18

(10.79–19.84)

64.83

(51.07–85.63)

1022.01

(576.63–2339.51)

1.07 ± 0.16

2.65

0.61

1.18

12

13.01

(9.06–17.18)

56.28

(44.46–73.51)

910.24

(520.08–2042.58)

1.06 ± 0.14

1.84

0.76

1.36

13

19.60

(14.55–24.98)

76.61

(60.65–101.22)

1021.48

(590.93–2235.17)

1.13 ± 0.19

2.54

0.63

1

14

11.48

(7.84–15.35)

50.65

(40.01–65.79)

849.25

(487.15–1896.27)

1.04 ± 0.14

2.04

0.72

1.51

15

2.80

(1.59–4.18)

10.76

(7.89–13.80)

138.76

(98.29 -222.48)

1.15 ± 0.11

9.40

0.05

7.11

16

3.33

(1.83–5.07)

15.32

(11.30 -19.76)

278.27

(178.64–524.78)

1.01 ± 0.16

5.99

0.19

5.00

17

2.65

(1.53–3.95)

9.87

(7.23–12.67)

119.68

(87.43–182.03)

1.18 ± 0.10

6.20

0.18

7.76

Chlorfenapyr

3.11

(1.69–4.75)

14.03

(10.27–18.12)

245.43

(160.17–450.60)

1.03 ± 0.14

5.69

0.22

5.46

  1. a(F.l.) Fiducial limits.
  2. bSlope of the concentration-mortality regression line ± standard error.
  3. cX2 chi-square significant at P < 0.05.
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