Figure 1
From: The syntaxin-binding protein STXBP5 regulates progerin expression
The SNARE proteins STXBP5 and STXBP6 were identified through analysis of public datasets. Volcano plots showing the genetic differences between early hHEPs and late hHEPs (A), and between WM 3835 treated late hHEPs and late hHEPs (B). (C) Venn diagram showing the overlap between the upregulated and downregulated genes in early hHEPs and WM 3835-treated late hHEPs compared with late hHEPs, as determined by RNA-seq analysis. STXBP5 and STXBP6 are marked with arrows.
