Table 4 Comparison of baseline norepinephrine level, oxidative stress, and mitochondrial function between clinical AF and subclinical AF patients.
Laboratory parameters | Clinical AF (n = 36) | Subclinical AF (n = 18) | P value |
|---|---|---|---|
Norepinephrine level (pg/mL) | 303.5, 231.7–442.0 | 360.1, 214.8–529.0 | 0.556 |
Cellular oxidative stress (arbitrary unit) | 24840.0, 20980.0–30989.0 | 25418.0, 21366.0–31390.0 | 0.810 |
Mitochondrial oxidative stress (arbitrary unit) | 3447.0, 2622.8–4201.8 | 2531.5, 2204.2–4428.5 | 0.281 |
Mitochondrial mass (arbitrary unit) | 26538.0, 19183.2–37901.2 | 21107.0, 15225.5–32483.5 | 0.168 |
Mitochondrial oxidative stress/ mass ratio | 0.1, 0.1–0.2 | 0.1, 0.1–0.2 | 0.780 |
Basal respiration (pMol/min) | 72.1, 47.4–94.4 | 97.2, 52.1–152.6 | 0.022* |
Maximal respiration (pMol/min) | 101.0, 46.0–175.1 | 112.5, 31.9–208.8 | 0.452 |
Proton leak (pMol/min) | 22.6, 6.0–36.0 | 29.1, 12.2–58.8 | 0.407 |
ATP production (pMol/min) | 57.3, 24.7–73.2 | 78.6, 45.7–112.0 | 0.015* |
%Spare respiration capacity | 157.4, 134.1–206.8 | 152.0, 119.8–204.5 | 0.622 |
%Coupling efficiency | 79.3, 73.1–90.4 | 83.3, 79.3–93.1 | 0.198 |
