Fig. 2

Genetically predicted causal associations between CUD and neurological disorders. MR results where significant causal associations exist are indicated using light salmon pink colors and are bolded. MR results that are not causally causal associations are indicated in blue color. AS, All Stroke; IS, Ischemic stroke; LAS, large-artery atherosclerotic stroke; SVS, small-vessel stroke; CES, cardioembolic stroke; ICH, Intracerebral Hemorrhage; AD, Alzheimer’s disease.