Table 4 Risk of 30-day, 90-day and 180-day mortality among individuals with chronic obstructive pulmonary disease hospitalized with community-acquired pneumonia by tertiles of health-related quality of life at admission.

Mortality	OR (95% CI) Unadjusted (n = 147)	P	OR (95% CI) Adjusted Complete case (n = 87)	P	OR (95% CI) Adjusted Imputed data (n = 147)	P
30-day
EQ utility score	2.68 (0.3; 27.0)	0.40	1.1 (0.0; 24.7)	0.98	2.53 (0.2; 33.6)	0.48
Lowest tertile	Ref.		Ref.		Ref.
Middle tertile	1.0 (0.3; 3.7)	1.00	0.24 (0.0; 2.0)	0.18	0.65 (01; 3.2)	0.60
Highest tertile	1.0 (0.3; 3.7)	1.00	0.24 (0.0; 1.8)	0.16	0.90 (0.2; 4.0)	0.90
90-day
EQ utility score	0.56 (0.1; 3.4)	0.52	0.16 (0.0; 2.3)	0.18	0.50 (0.1; 3.9)	0.51
Lowest tertile	Ref.		Ref.		Ref.
Middle tertile	0.44 (0.1; 1.4)	0.17	0.14 (0.0; 0.9)	0.04*	0.30 (0.1; 1.2)	0.09
Highest tertile	0.54 (0.2; 1.6)	0.28	0.12 (0.0; 0.8)	0.03*	0.47 (0.1; 1.6)	0.23
180-day
EQ utility score	0.27 (0.1; 1.2)	0.09	0.16 (0.0; 1.8)	0.14	0.23 (0.0; 1.3)	0.10
Lowest tertile	Ref.		Ref.		Ref.
Middle tertile	0.37 (0.1; 0.96)	0.04*	0.18 (0.0; 0.97)	0.046*	0.20 (0.1; 0.7)	0.01*
Highest tertile	0.37 (0.1; 0.96)	0.04*	0.18 (0.0; 0.9)	0.04*	0.31 (0.1; 0.9)	0.04*

Health-related quality of life was measured as the total utility score derived from the EuroQoL (EQ) 5D-5L questionnaire. Logistic regression was fitted for mortality 30, 90 and 180 days after discharge. Estimates shown are odds ratios (OR) with corresponding 95% confidence intervals (CI) and p-value. The first column shows the unadjusted model. The second column shows the adjusted complete case model. The third column shows the adjusted model with imputed variables. The adjusted models include the following variables: age, sex, FEV1 (pulmonary function), CURB-65 (initial severity of CAP), Charlson comorbidity index, and nutritional status (undernourished, well-nourished, overweight, and obese). Values were imputed in FEV1 (n = 18), CURB-65 (n = 16), and nutritional status (n = 32). *Statistically significant (p < 0.05).

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