Table 3 Effects of melatonin on embryo development competence after in vitro fertilization.

From: Melatonin decreases excessive polyspermy for single oocyte in pigs through the MT2 receptor

Groups

No. of embryos 

Cultured1

No. of embryos developed to (Mean ± SEM, %)

Total cell numbers/blastocyst

Cleavage (%)

Blastocyst (%)

Control

176

135

(72.0 ± 0.4)

62

(35.1 ± 0.7)b

68.4 ± 2.2

Melatonin2

186

145

(74.6 ± 1.5)

78

(42.1 ± 1.0)a

70.6 ± 3.9

Mtn + Lu3

172

128

(71.5 ± 1.2)

58

(32.7 ± 1.0)b

68.7 ± 3.4

Mtn + 4P4

159

123

(74.1 ± 2.1)

51

(32.7 ± 2.3)b

70.2 ± 0.9

  1. a, b Values with different superscript letters indicate statistical significance (P < 0.05).
  2. 1The experiment was replicated on three occasions.
  3. 2Melatonin: 10−9 M Melatonin.
  4. 3Mtn + Lu: 10−9 M Melatonin + 10−9 M Luzindole.
  5. 4Mtn + 4P: 10−9 M Melatonin + 10−9 M 4-P-PDOT.
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