Fig. 4 | Scientific Reports

Fig. 4

From: Integrating holotomography and deep learning for rapid detection of NPM1 mutations in AML

Fig. 4

Deep learning classification of myeloblast holotomography (HT) images for NPM1 mutation status. (a) Validation result of the deep learning classifier on myeloblast HT images of four NPM1 wild-type patients. (b) Validation result of the deep learning classifier on myeloblast HT images of four NPM1 mutant patients. (c) Receiver operating characteristic curve representing the performance of patient-wise NPM1 mutation screening based on different threshold positive prediction ratios. (d) Plot of deep learning output values corresponding to the two classes (wild-type and mutant). Each data point represents an individual myeloblast HT image. The dashed diagonal line indicates the boundary where the two output values are equal.

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