Table 2 The bivariable associations between infant or unit characteristic and the dosing-measured weights percent difference.

From: Factors influencing the determination of dosing weight in the neonatal intensive care unit (NICU)

Infant or Unit Characteristic

Percent difference (95% Confidence Interval)*

p-value

Birth weight (kg)

2.0 (0.1, 3.8)

0.035

Small for gestational age

0.1 (-1.6, 1.8)

0.916

Patent ductus arteriosus

-0.9 (-2.0, 0.2)

0.115

Necrotizing enterocolitis or spontaneous intestinal perforation

-0.4 (-1.8, 1.1)

0.612

Intubated on day 28

-1.2 (-2.3, -0.1)

0.038

Blood stream infection

0.2 (-1.3, 1.7)

0.794

Highest creatinine in mg/dL

-5.6 (-7.1, -4.0)

< 0.001

Lowest sodium in mEq/L

0.1 (-0.03, 0.2)

0.179

3DMA of daily fluid intake, 10mL/kg/day

0.3 (0.2, 0.4)

< 0.001

3DMA of daily urine output, mL/kg/hour

0.8 (0.6, 1.0)

< 0.001

Maternal steroids

-0.2 (-1.2, 0.9)

0.780

NSAIDs

-0.9 (-2.0, 0.2)

0.104

Caffeine

-0.1 (-1.6, 1.3)

0.872

Resident team (referent to nurse practitioner team)

0.1 (-1.0, 1.3)

0.797

  1. 3DMA, 3-day moving average
  2. *Mixed effects linear regression reported as beta coefficient (percent difference) and p-value