Table 4 The bivariable associations between infant or unit characteristic and the dosing weight updates.

From: Factors influencing the determination of dosing weight in the neonatal intensive care unit (NICU)

Infant or Unit characteristics

Odds Ratio (95% Confidence Interval)*

p-value

Birth weight (kg)

0.9 (0.7, 1.2)

0.433

Small for gestational age

1.0 (0.8, 1.3)

0.901

Patent ductus arteriosus

1.0 (0.8, 1.1)

0.720

Necrotizing enterocolitis or spontaneous intestinal perforation

1.0 (0.8, 1.3)

0.823

Intubated on day 28

1.1 (0.9, 1.3)

0.468

Blood stream infection

1.1 (0.9, 1.4)

0.445

Highest creatinine in mg/dL

0.9 (0.7, 1.2)

0.494

Lowest sodium in mEq/L

1.0 (1.0, 1.0)

0.593

3DMA of daily fluid intake in 10mL/kg/day

1.0 (0.9, 1.0)

0.154

3DMA of daily urine output in mL/kg/hour

1.0 (1.0, 1.1)

0.466

Maternal steroids

1.1 (0.9, 1.3)

0.339

Ibuprofen or indomethacin

1.0 (0.9, 1.2)

0.881

Caffeine

1.1 (0.9, 1.3)

0.472

Monday or Friday

9.6 (8.0, 11.5)

< 0.001

Saturday or Sunday

0.2 (0.2, 0.3)

< 0.001

Resident team (referent to nurse practitioner team)

1.1 (0.9, 1.3)

0.304

  1. 3DMA, 3-day moving average
  2. *Mixed effects logistic regression reported as an odds ratio and p-value