Table 3 Comparison of baseline optical coherence tomography angiography quantitative parameters between patient subgroups based on visual acuity changes at 3 months.

From: Baseline optical coherence tomography angiography biomarkers predict visual outcomes in treatment-naïve neovascular age-related macular degeneration patients

Variables

BCVA change in month 3

15 ≥ ETDRS letters

15 < ETDRS letters

P

Mean ± SD

Mean ± SD

Explant area (mm²)

1.780 ± 1.457

1.344 ± 0.791

0.393

Vessels area (mm²)

0.957 ± 0.849

0.801 ± 0.444

0.590

Vessels percentage area

54.82 ± 10.08

62.49 ± 6.89

0.049*

Total number of junctions

88.95 ± 90.93

73.25 ± 44.77

0.598

Junctions density (n/mm)

0.446 ± 0.109

0.526 ± 0.052

0.167

Total vessels length (mm)

15.867 ± 14.540

12.829 ± 7.555

0.540

Average vessels length (mm)

6.187 ± 8.024

3.827 ± 2.647

0.408

Total number of end points

25.66 ± 15.45

21.88 ± 11.53

0.465

Mean lacunarity

0.170 ± 0.079

0.096 ± 0.017

0.037*

Fractal dimension

1.499 ± 0.090

1.554 ± 0.077

0.089

  1. The reported P values are adjusted for age and sex using multiple logistic regression analysis.
  2. Statistically significant P values are indicated by an asterisk (*).
  3. BCVA (best corrected visual acuity), ETDRS (early treatment diabetic retinopathy study).
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