Table 4 Comparison of baseline optical coherence tomography angiography quantitative parameters between patient subgroups based on visual acuity changes at 12 months.

From: Baseline optical coherence tomography angiography biomarkers predict visual outcomes in treatment-naïve neovascular age-related macular degeneration patients

Variables

BCVA change in month 12

15 ≥ ETDRS letters

15 < ETDRS letters

P

Mean ± SD

Mean ± SD

Explant area (mm²)

1.790 ± 1.544

1.507 ± 0.857

0.552

Vessels area (mm²)

0.971 ± 0.908

0.835 ± 0.435

0.620

Vessels percentage area

55.01 ± 10.47

58.76 ± 8.53

0.270

Total number of junctions

91.75 ± 97.47

73.57 ± 42.82

0.536

Junctions density (n/mm)

0.477 ± 0.116

0.477 ± 0.072

0.973

Total vessels length (mm)

16.239 ± 15.553

13.280 ± 7.327

0.528

Average vessels length (mm)

6.747 ± 8.640

3.558 ± 2.055

0.219

Total number of end points

25.78 ± 15.79

23.21 ± 12.63

0.632

Mean lacunarity

0.159 ± 0.076

0.153 ± 0.084

0.800

Fractal dimension

1.500 ± 0.096

1.530 ± 0.072

0.330

  1. The reported P values are adjusted for age and sex using multiple logistic regression analysis.
  2. BCVA (best corrected visual acuity), ETDRS (early treatment diabetic retinopathy study).
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