Table 1 Influencing input parameters in simulation of aerosol deposition in airway within the three main groups of Functional respiratory imaging (FRI), inhalation and device/active pharmaceutical ingredient (API), and their combinations.
From: Rapid deposition analysis of inhaled aerosols in human airways
Main group | Input parameter |
|---|---|
FRI | \(\:{A}_{branch},\:{A}_{trachea}\), \(\:{L}_{ch},\)\(\:{L}_{ch,ref},\)\(\:{V}_{branch}\), \(\:{V}_{branch,\:total}\), \(\:{V}_{TLC}\), \(\:{V}_{FRC}\), \(\:{V}_{FRC,\:total}\), \(\:{V}_{TLC,total},\)\(\:{N}_{outlet}\), \(\:{T}_{airway}\), \(\:s\), \(\:Tor\) |
Inhalation | \(\:PIF\), \(\:{Q}_{inh},\:\phi\:\), \(\:\:{t}_{inh},\:{TV}_{inh}\), \(\:u\), \(\:{\rho\:}_{a}\), \(\:{\mu\:}_{a}\), \(\:{T}_{air}\), \(\:{\upsilon\:}_{a}\), \(\:{t}_{exh}\) |
Device/API | \(\:FPF\), \(\:MMAD\), \(\:GSD\), \(\:{\rho\:}_{p}\), \(\:{t}_{inj},\:\alpha\:,\:{u}_{plume}\), \(\:\sigma\:\), \(\:{k}_{d}\), \(\:{d}_{nozzle}\) |
N.A. | \(\:g\) |
