Table 5 Multifactorial analysis: risk of bleeding and thrombosis in Haemato-Oncology.

From: Clinical analysis of bleeding and thrombotic events in haematological-oncology patients with severe thrombocytopenia and a high risk of thrombosis

Dependent variable

variables

B

Standard error

Wald coefficient

OR

95% CI

P value

Bleeding events

Type of haematological malignancies

  

9.158

  

0.027

Lymphomas

-2.102

0.743

8.016

0.122

0.029–0.524

0.005

Plasma cell diseases

-0.355

0.753

0.222

0.701

0.160–3.069

0.637

CCI score

0.286

0.121

5.560

1.331

1.049–1.687

0.018

Minimum platelet count

-0.078

0.018

18.175

0.925

0.893–0.959

<0.001

Thrombosis events

History of thrombosis

2.850

1.194

5.701

17.284

1.666-179.291

0.017

2 intravenous catheter lumens

2.061

1.039

3.934

7.852

1.025–60.169

0.047

Sedatives

3.554

1.579

5.065

34.969

1.582-772.771

0.024

  1. Bleeding events: haematological malignancy type, cellular origin, coinfection of the lungs, CCI score, initial platelet count, initial PT, minimum platelet count, type of intravenous catheter, number of intravenous catheter lumens, and length of time the intravenous catheter was left in place, may be risk factors for bleeding. They were set as independent variables and analysed via binary logistic regression via the input method with the inclusion criterion P<0.05 and the exclusion criterion P>0.1.
  2. Thrombosis events: history of thrombosis, type of haematological malignancy, initial platelet count, number of venous catheter lumens, parenteral nutrition, sedation, and Auto-HSCT may be risk factors for thrombosis. They were set as independent variables and analysed via binary logistic regression via the input method with the inclusion criterion P<0.05 and the exclusion criterion P>0.1.
  3. CCI, Charlson Comorbidity Index.
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