Table 1 Lipid transport-associated proteins upregulated in organotypic 3D cultures of Hs578t breast cancer cells in coculture with adipocytes.
Protein | n.log10 (ANOVA) | UniProt accession number | Function in breast cancer | Reference |
|---|---|---|---|---|
PITPNM2 | 4.03 | Q9BZ72 | Unknown | N/A |
ATP2C1 | 4.03 | B4E2Q0 | Promote microcalcifications in vitro in breast cancer cells | [24] |
RNF213 | 3.96 | Q63HN8 | Promote tumor survival during hypoxia | [25] |
PON1 | 3.84 | P27169 | Marker of short-term death in breast cancer recurrence | [26] |
APOB | 3.78 | P04114 | Risk factor for the development of intraocular metastases | [27] |
ABCA12 | 3.30 | Q86UK0 | Marker of progression and response to chemotherapy | [28] |
ABCA9 | 3.19 | H0Y4U7 | Promotes cancer progression | [29] |
PLA2G6 | 2.95 | A0A590UJC7 | Unknown | N/A |
ABCA8 | 2.45 | O94911 | Marker of progression and response to chemotherapy | [28] |
HDLBP | 1.48 | Q00341 | Unknown | N/A |
ATP8B4 | 1.34 | Q8TF62 | Unknown | N/A |