Fig. 1

The volcano plot shows the differential expression of circRNAs, miRNAs, and mRNAs between the normal culture group and the osteogenic induction group hBMSCs. (a) DE-circRNAs (P < 0.05, |log2 fold change|> 0.5); (b) DE-miRNAs (P < 0.05, |log2 fold change|> 0.5); (c) DE-mRNAs(P < 0.05, |log2 fold change|> 1.2); Red dots represent upregulated gene expression, blue dots represent downregulated gene expression.