Fig. 4
From: DTL promotes the growth and migration of melanoma cells through the ERK/E2F1/BUB1 axis
DTL promotes the malignancy of melanoma in vivo. (A) Forced DTL expression greatly enhanced the size and weight of xenograft tumor. (B) Depleted DTL considerably decreased the volume and weight of the xenograft tumor. (C) IHC results indicated that xenografts derived from Sk-Mel-28-DTL cells had a higher percentage of Ki67- and CD31-positive cells compared to Sk-Mel-28-shDTL. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. NC normal control.
