Table 1 Distribution of 77 colorectal cancer (CRC), 72 intestinal adenoma (IA) and 76 healthy controls by selected characteristics; Italy 2017–2019.

From: Serum zonulin and colorectal cancer risk

Characteristic

CRC

IA

Healthy controls

χ 2

p-value

Study center

   

0.88

 Niguarda

44 (57.1%)

41 (56.9)

46 (60.5)

 

 Policlinico

33 (42.9%)

31 (43.1)

30 (39.5)

 

Sex

   

0.90

 Male

49 (63.6%)

47 (65.3)

51 (67.1)

 

 Female

28 (36.4%)

25 (34.7)

25 (32.9)

 

Age group

   

0.60

 < 50

9 (11.7%)

3 (4.2)

6 (7.9)

 

 50–59

15 (19.5%)

13 (18.1)

19 (25.0)

 

 60–69

20 (26.0%)

25 (34.7)

16 (21.1)

 

 70–79

24 (31.2%)

24 (33.3)

26 (34.2)

 

 ≥ 80

9 (11.7%)

7 (9.7)

9 (11.8)

 

Mean (SD)

65.7 (12.2)

66.6 (10.4)

65.3 (12.5)

0.81a

Education (years)b

   

0.50

 < 7

17 (22.1%)

14 (19.4)

9 (11.8)

 

 7–11

18 (23.4%)

21 (29.2)

21 (29.2)

 

 ≥ 12

41 (53.9%)

37 (51.4)

37 (51.4)

 

Body mass index (kg/m2)

   

0.91

 < 25

40 (51.9%)

35 (48.6%)

37 (49.3%)

 

 ≥ 25

37 (48.1%)

37 (51.4%)

38 (50.7%)

 

Mean (SD)

25.2 (4.2)

25.6 (3.7)

25.8 (3.6)

0.66a

Diabetes

   

0.87

 Yes

9 (11.7)

10 (13.9)

11 (14.5)

 

 No

68 (88.3)

62 (86.1)

65 (85.5)

 
  1. ap-value from Anova for heterogeneity.
  2. bThe sum does not add up to the total because of one missing value.