Table 1 Baseline characteristics of the study participants.

From: The neutrophil–lymphocyte ratio is associated with all-cause and cardiovascular mortality in cardiovascular patients

Variables

Total

(n=2239)

Lower NLR

(n=1575)

Higher NLR

(n=664)

P value

Age, years, Mean ± SD

66.6 ± 12.6

65.2 ± 12.9

70.1 ± 11.4

< 0.001

Sex, n (%)

   

0.002

Male

1277 (57.0)

865 (54.9)

412 (62)

 

Female

962 (43.0)

710 (45.1)

252 (38)

 

Race/Ethnicity, n (%)

   

< 0.001

Non-Hispanic White

1266 (56.5)

819 (52)

447 (67.3)

 

Non-Hispanic Black

461 (20.6)

387 (24.6)

74 (11.1)

 

Mexican American

243 (10.9)

178 (11.3)

65 (9.8)

 

Others

269 (12.0)

191 (12.1)

78 (11.7)

 

Education level, n (%)

   

0.389

Less than high school

789 (35.2)

560 (35.6)

229 (34.5)

 

High school or equivalent

534 (23.8)

363 (23)

171 (25.8)

 

College or above

916 (40.9)

652 (41.4)

264 (39.8)

 

Marital status, n (%)

   

0.073

Married or living with a partner

1299 (58.0)

918 (58.3)

381 (57.4)

 

 Never married

144 (6.4)

112 (7.1)

32 (4.8)

 

 Widowed, divorced, separated

796 (35.6)

545 (34.6)

251 (37.8)

 

PIR, n (%)

   

0.199

≤ 1.30

705 (31.5)

515 (32.7)

190 (28.6)

 

1.31–3.50

865 (38.6)

589 (37.4)

276 (41.6)

 

> 3.50

478 (21.3)

335 (21.3)

143 (21.5)

 

unknown

191 (8.5)

136 (8.6)

55 (8.3)

 

Smoking statues, n (%)

   

0.158

 Current smoker

477 (21.3)

344 (21.8)

133 (20)

 

 Former smoker

906 (40.5)

617 (39.2)

289 (43.5)

 

 Never smoker

856 (38.2)

614 (39)

242 (36.4)

 

Drinking status, n (%)

   

0.635

 Yes

1577 (70.4)

1114 (70.7)

463 (69.7)

 

 No

662 (29.6)

461 (29.3)

201 (30.3)

 

BMI category, n (%)

   

0.092

 < 25

511 (22.8)

341 (21.7)

170 (25.6)

 

 25.1–30

747 (33.4)

526 (33.4)

221 (33.3)

 

 ≥ 30

981 (43.8)

708 (45)

273 (41.1)

 

Diabetes, n (%)

   

0.024

 Yes

934 (41.7)

633 (40.2)

301 (45.3)

 

 No

1305 (58.3)

942 (59.8)

363 (54.7)

 

Hypertension, n (%)

   

0.005

 Yes

1729 (77.2)

1191 (75.6)

538 (81)

 

 No

510 (22.8)

384 (24.4)

126 (19)

 

LDL cholesterol, mmol/L, Mean ± SD

2.7 ± 1.0

2.8 ± 1.0

2.5 ± 1.0

< 0.001

eGFR, ml/(min·1.73m^2), Mean ± SD

75.0 ± 23.8

77.4 ± 23.0

69.4 ± 24.8

< 0.001

White blood cell, 1000 cells/uL, Mean ± SD

7.2 ± 3.4

6.9 ± 3.7

7.9 ± 2.3

< 0.001

NLR, Mean ± SD

2.6 ± 1.5

1.9 ± 0.6

4.3 ± 1.8

< 0.001

  1. Abbreviations: NLR, neutrophil-lymphocyte ratio; SD, standard deviation; PIR, poverty income ratio; BMI, body mass index; LDL cholesterol, low density lipoprotein-cholesterol; eGFR, estimated glomerular filtration rate.
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