Fig. 7

Comparisons of microbiota derived potentials metabolic functions between (A) established SLE (11-month-old pristane and knockout) and young healthy (4-month-old healthy), (B) established SLE and preclinical SLE (4-month-old pristane and knockout), (C) established SLE and old healthy (11-month-old healthy), and (D) the established SLE mice induced by pristane (11-month-old pristane) and FcGRIIb^−/− (11-month-old knockout). The significant statistics were performed using Welch’s t-test 2-sided method (p ≤ 0.05).