Table 2 The result of functional enrichment analysis of DMPs identified in EWAS (FDR ≤ 0.05, N ≥ 2).
From: MethylCallR : a comprehensive analysis framework for Illumina Methylation Beadchip
Category | ID | Description | N | p-value | FDR | |
|---|---|---|---|---|---|---|
GO | BP | GO:0051607 | defense response to virus | 13 | 8.11E-10 | 9.26E-06 |
GO:0140546 | defense response to symbiont | 13 | 8.20E-10 | 9.26E-06 | ||
GO:0009615 | response to virus | 13 | 3.03E-08 | 2.28E-04 | ||
GO:0098542 | defense response to other organism | 18 | 7.51E-07 | 4.24E-03 | ||
GO:0034340 | response to type I interferon | 6 | 1.14E-06 | 5.16E-03 | ||
GO:0051707 | response to other organism | 20 | 2.27E-06 | 7.45E-03 | ||
GO:0043207 | response to external biotic stimulus | 20 | 2.31E-06 | 7.45E-03 | ||
GO:0140888 | interferon-mediated signaling pathway | 6 | 2.93E-06 | 8.27E-03 | ||
GO:0009607 | response to biotic stimulus | 20 | 3.63E-06 | 9.11E-03 | ||
GO:0045087 | innate immune response | 15 | 4.43E-06 | 1.00E-02 | ||
GO:0016032 | viral process | 11 | 6.05E-06 | 1.16E-02 | ||
GO:0002230 | positive regulation of defense response to virus by host | 4 | 6.17E-06 | 1.16E-02 | ||
GO:0060337 | type I interferon-mediated signaling pathway | 5 | 1.37E-05 | 2.24E-02 | ||
GO:0071357 | cellular response to type I interferon | 5 | 1.39E-05 | 2.24E-02 | ||
GO:0019079 | viral genome replication | 6 | 1.79E-05 | 2.53E-02 | ||
GO:0044419 | biological process involved in interspecies interaction between organisms | 20 | 1.80E-05 | 2.53E-02 | ||
GO:0045069 | regulation of viral genome replication | 5 | 2.71E-05 | 3.60E-02 | ||
GO:1,903,900 | regulation of viral life cycle | 6 | 2.98E-05 | 3.74E-02 | ||
GO:0006952 | defense response | 20 | 3.54E-05 | 4.05E-02 | ||
GO:0050691 | regulation of defense response to virus by host | 4 | 3.59E-05 | 4.05E-02 | ||
GO:0019221 | cytokine-mediated signaling pathway | 10 | 4.60E-05 | 4.94E-02 | ||
