Fig. 3

Genotype-specific efficacy of wMel. The protective efficacy was calculated as 100x (1-aggregate odds ratio), overall and by serotype as reported previously 16, and by genotype. Circles indicate point estimates and lines the 95% confidence interval. *Genotypes with too few observations to generate meaningful confidence intervals. ^DENV-1 and DENV-2 genotype-specific VCDs sum to fewer than the serotype totals because sequencing quality and coverage did not permit genotype assignment for all cases, particularly in instances of coinfection.