Table 1 Clinical and radiological characteristics of patients, tumor characteristics, and methylation status from both training and validation sets.
Feature | Description | Training | Validation | p-value |
|---|---|---|---|---|
Tumor location | 0.01 | |||
Type 1 (in contact with subventricular zone (SVZ) and cortex) | 65(65) | 21(45.7) | ||
Type 2 (contact with SVZ but NOT cortex) | 4(4) | 6(13) | ||
Type 3 (Contact ONLY with cortex) | 31(31) | 17(37) | ||
NA | 0(0) | 2(4.3) | ||
Laterality | 0.33 | |||
Right | 45(45) | 16 (34.8) | ||
Left | 48(48) | 24(52.2) | ||
Bilateral | 7(7) | 6(13) | ||
Well defined bordes | < 0.01 | |||
Yes | 18(18) | 19(41.3) | ||
No | 82(82) | 27(58.7) | ||
NA | 0(0) | 0(0) | ||
Multifocality | 0.07 | |||
Yes | 28(28) | 9(19.6) | ||
No | 72(72) | 35(76.1) | ||
NA | 0(0) | 2(4.3) | ||
Midline crossing | 0.1 | |||
Yes | 32(32) | 13(28.3) | ||
No | 68(68) | 31(67.4) | ||
NA | 0(0) | 2(4.3) | ||
Greatest dimension of contrast enhancing lesion | 0.03 | |||
< 1.5 cm | 5(5) | 3(6.5) | ||
≥ 1.5 cm | 95(95) | 40(87) | ||
NA | 0(0) | 3(6.5) | ||
IDH 1/2 status | 0.01 | |||
Wildtype | 100(100) | 42(91.3) | ||
Mutated | 0(0) | 4(8.7) | ||
Gender | 0.02 | |||
Female | 41(41) | 29(63) | ||
Male | 59(59) | 17(37) | ||
MGMT status | 0.7 | |||
Unmethylated | 61(61) | 30(65.2) | ||
Methylated | 39(39) | 16(34.8) |