Fig. 4 | Scientific Reports

Fig. 4

From: Exploration of common pathogenesis and candidate hub genes between HIV and monkeypox co-infection using bioinformatics and machine learning

Fig. 4

Machine learning in screening candidate hub genes for HIV and monkeypox co-infection. (A, B) Key genes screening in the Lasso model; the number of key genes (n = 11) corresponding to the λ-se was the most suitable in HIV and monkeypox co-infection. (C, D) Top 10 genes selected based on the random forest algorithm; (E) Venn diagram showing that 7 candidate hub genes were identified via the above two algorithms. (F) The ROC curve of each hub gene (MX2, ADAR, POLR2H, RPL5, IFI16, IFIT2 and RPS5).

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