Table 4 Continuous 24-h ECG monitoring and heart rate variability at 6 months in both groups of age.

From: Effect of age on clinical impact and mid-term denervation in patients undergoing cardioneuroablation

 

< 50 years (n = 17)

≥ 50 years (n = 33)

Pre CNA

Post CNA

p-value

Pre CNA

Post CNA

p-value

Minimum HR (bpm)

41.3 ± 9.4

54.6 ± 14.1

0.017

41.6 ± 9.5

52.8 ± 14.7

< 0.001

Median HR (bpm)

73.6 ± 19.7

78.8 ± 10.8

0.623

69.6 ± 11.8

74.9 ± 14.7

0.012

Maximum HR (bpm)

124.2 ± 24.6

122.7 ± 17.4

0.362

112.1 ± 22.9

109.7 ± 17.3

0.588

SDNN 24 h (ms)

165.5 ± 64.6

102.5 ± 42.4

0.069

145.6 ± 35.6

105.6 ± 37.8

< 0.001

RMSSD (ms)

43 (28–72)

17 (11–24)

0.014

27 (21–37)

21 (13–25)

< 0.001

PNN50 (%)

12 (8–32)

1 (0–5)

0.018

5 (3–15)

3 (1–5)

0.007

VLF (ms2)

3553 (2509–4900)

726 (245–1733)

0.028

1925 (1236–2783)

257 (152–592)

< 0.001

LF (ms2)

1139 (1032–1308)

136 (43–534)

0.018

469 (358–1039)

53 (31–171)

< 0.001

HF (ms2)

333 (272–599)

82 (15–141)

0.018

116 (93–211)

54 (17–94)

< 0.001

  1. CNA cardioneuroablation, HR hear rate, SDNN SD of NN intervals, RMSSD root mean square of successive RR interval differences, PNN50 percentage of successive RR intervals that differ by > 50 ms, VLF absolute power of the very-low-frequency band (0.0033–0.04 Hz), LF absolute power of the low-frequency band (0.04–0.15 Hz), HF absolute power of the high-frequency band (0.15–0.4 Hz).