Table 3 Cell lines used in this study. α-Syn expression was tested by Western blotting and qPCR.

SK-MEL-28

This cell line was isolated from skin tissue from a 51-year-old, male with malignant melanoma

Y

SK-MEL-28 SNCA-KO clones KO8, KO9

SNCA knocked out in SK-MEL-28 cells using CRISPR/Cas9

N

³⁴

SK-MEL-28 SNCA-KI clones KI8, KI9

SNCA cDNA was re-introduced into the KO clones using lenti virus

Y

³⁴

WM983B

This cell line was established from an inguinal node metastatic site in a 54-year-old male patient

Y

WM983B SNCA-KO clones 1 and 2

SNCA knocked out in WM983B cells using CRISPR/Cas9

N

_{This study}