Table 1 Screening of 20 gut microbiota associated with Guillain–barre syndrome by IVW.
Exposure | Method | nsnp | P-valve | OR | OR_lci95 | OR_uci95 |
|---|---|---|---|---|---|---|
PWY0.1298..superpathway.of.pyrimidine.deoxyribonucleosides.degradation | IVW | 14 | 0.001901 | 0.450788 | 0.272627 | 0.745377 |
GLCMANNANAUT.PWY..superpathway.of.N.acetylglucosamine..N.acetylmannosamine.and.N.acetylneuraminate.degradation | IVW | 8 | 0.004551 | 0.405104 | 0.217004 | 0.75625 |
PWY.5121..superpathway.of.geranylgeranyl.diphosphate.biosynthesis.II..via.MEP | IVW | 13 | 0.00822 | 1.747626 | 1.155171 | 2.643935 |
k_Bacteria.p_Firmicutes.c_Erysipelotrichia.o_Erysipelotrichales.f_Erysipelotrichaceae.g_Erysipelotrichaceae_noname | IVW | 12 | 0.012567 | 1.500125 | 1.090967 | 2.062734 |
k_Bacteria.p_Firmicutes | IVW | 6 | 0.016822 | 0.420504 | 0.206683 | 0.855533 |
PWY0.781..aspartate.superpathway | IVW | 11 | 0.017151 | 0.530923 | 0.315439 | 0.893608 |
PWY_NAD.BIOSYNTHESIS.II..NAD.salvage.pathway.II | IVW | 13 | 0.019233 | 0.66219 | 0.46892 | 0.935117 |
k_Bacteria.p_Firmicutes.c_Clostridia.o_Clostridiales.f_Lachnospiraceae.g_Butyrivibrio.s_Butyrivibrio_crossotus | IVW | 11 | 0.023176 | 0.775336 | 0.622434 | 0.965799 |
POLYAMSYN.PWY..superpathway.of.polyamine.biosynthesis.I | IVW | 8 | 0.026577 | 0.502378 | 0.273401 | 0.923128 |
PWY.6317..galactose.degradation.I..Leloir.pathway | IVW | 10 | 0.02855 | 0.549137 | 0.321117 | 0.939071 |
k_Bacteria.p_Firmicutes.c_Clostridia.o_Clostridiales.f_Lachnospiraceae.g_Blautia.s_Ruminococcus_obeum | IVW | 13 | 0.03009 | 1.609731 | 1.046922 | 2.475099 |
k_Bacteria.p_Firmicutes.c_Clostridia.o_Clostridiales.f_Lachnospiraceae.g_Roseburia | IVW | 14 | 0.031424 | 1.605429 | 1.043068 | 2.47098 |
PWY.5918..superpathay.of.heme.biosynthesis.from.glutamate | IVW | 9 | 0.038818 | 1.614617 | 1.024911 | 2.543625 |
k_Bacteria.p_Actinobacteria.c_Actinobacteria.o_Bifidobacteriales.f_Bifidobacteriaceae.g_Bifidobacterium | IVW | 10 | 0.039705 | 1.672921 | 1.024515 | 2.731697 |
PWY.7219..adenosine.ribonucleotides.de.novo.biosynthesis | IVW | 13 | 0.045555 | 0.559496 | 0.316648 | 0.988594 |
k_Bacteria.p_Bacteroidetes.c_Bacteroidia.o_Bacteroidales.f_Bacteroidaceae.g_Bacteroides.s_Bacteroides_fragilis | IVW | 17 | 0.045926 | 1.322167 | 1.00506 | 1.739325 |
PWY.5104..L.isoleucine.biosynthesis.IV | IVW | 9 | 0.046053 | 1.759484 | 1.009935 | 3.065331 |
DTDPRHAMSYN.PWY..dTDP.L.rhamnose.biosynthesis.I | IVW | 8 | 0.047417 | 1.922903 | 1.007466 | 3.670154 |
PWY.6700..queuosine.biosynthesis | IVW | 16 | 0.049246 | 1.56706 | 1.001476 | 2.452058 |
PWY.7013..L.1.2.propanediol.degradation | IVW | 9 | 0.049383 | 0.771924 | 0.596281 | 0.999306 |