Table 1 Characteristics of the participants. The data are presented as medians (interquartile range [IQR]) and n (%). *: the Mann–Whitney U test was employed for the purpose of comparing two groups. Regional lymph node metastasis: Regional lymph node metastasis corresponds to N1 and N2 stages in the N staging system. Chemoradiotherapy: the patient underwent radiotherapy and chemotherapy. Robotic: Da Vinci Surgical Robot. HGB: hemoglobin; ALB: albumin; LARS: low anterior resection syndrome; CI: confidence interval.

From: Risk factors of the low anterior resection syndrome (LARS) after ileostomy reversal in rectal cancer patient

 

Major LARS

no/minor LARS

P values

N = 94

N = 511

Gender

  

0.649

Male

61 (64.89%)

319 (62.43%)

 

Female

33 (35.11%)

192 (37.57%)

 

Age (years)

62.00(56.00–67.00)

62.00 (54.00–67.00)

0.452*

T stage

  

0.695

T1

8 (8.51%)

41 (8.02%)

 

T2

21 (22.34%)

136 (26.61%)

 

T3

24 (25.53%)

106 (20.74%)

 

T4

41 (43.62%)

228 (44.62%)

 

N stage

  

0.016

N0

60 (63.83%)

364 (71.23%)

 

N1

21 (22.34%)

118 (23.09%)

 

N2

13 (13.83%)

29 (5.68%)

 

M stage

  

0.151

M0

94 (100.00%)

500 (97.85%)

 

M1

0 (0.00%)

11 (2.15%)

 

Regional lymph nodes metastasis

  

0.150

Yes

34 (36.17%)

147 (28.77%)

 

No

60 (63.83%)

364 (71.23%)

 

Tumor location (cm)

6.00 (5.00–7.00)

6.00 (5.00-7.50)

0.092*

Anastomotic height(cm)

2.00 (2.00–4.00)

3.00 (2.00–4.00)

< 0.001*

adjuvant chemotherapy

  

0.271

Yes

58 (61.70%)

284 (55.58%)

 

No

36 (38.30%)

227 (44.42%)

 

Pathological stage

  

0.150

I

23 (24.47%)

155 (30.33%)

 

II

37 (39.36%)

207 (40.51%)

 

III

34 (36.17%)

138 (27.01%)

 

IV

0 (0.00%)

11 (2.15%)

 

Surgical methods

  

0.636

Laparoscopic

85 (90.43%)

444 (86.89%)

 

Robotic

5(5.32%)

37(7.24%)

 

Open surgery

4 (4.26%)

30 (5.87%)

 

Treatment category

  

0.040

Chemoradiotherapy

30 (31.91%)

214 (41.88%)

 

Chemotherapy

40 (42.55%)

217 (42.47%)

 

No

24 (25.53%)

80 (15.66%)

 

HBG (g/L)

136.00 (121.03-146.38)

136.00 (126.00-146.60)

0.256*

ALB (g/L)

42.05 (39.00-44.35)

42.30 (40.40-44.15)

0.124*

Stoma closure intervals (days)

208.50 (168.25-273.75)

231.00 (181.00-286.00)

0.135*

Anastomotic leakage or abscess

  

1.000

Yes

0 (0.00%)

4 (0.78%)

 

No

94 (100.00%)

507 (99.22%)

 

Postoperative bowel obstruction

  

0.398

Yes

1 (1.06%)

2 (0.39%)

 

No

93 (98.94%)

509 (99.61%)

 

Bleeding

  

1.000

Anastomotic bleeding

0 (0.00%)

3 (0.59%)

 

Intra-abdominal bleeding

0 (0.00%)

1 (0.20%)

 

No

94 (100.00%)

507 (99.22%)