Fig. 2

Activation extent and spatial overlap. (a) We compared the number of voxels with significant activation for each task and for each group. Individual participants are labeled with circles as well as their subject codes. Gray lines connect the data points for the different tasks for the same participant. Brackets are labeled with the p-values from two-tailed t-tests (paired within-group, independent samples between-groups). See Supplementary Fig. S2 for Spearman correlations on the number of active voxels for each task in LHPS participants and controls. (b) The Dice Coefficient averages are shown for individual participants (circles and subject codes) within each group: in blue, the symmetry of task activations in individual controls; in green, the overlap of task activations in individual LHPS participants. Brackets are labeled with the p-values from independent samples t-tests. See Supplementary Fig. S3 for the Dice Coefficient relationships at each individual top voxel level and Supplementary Fig. S4 for the Dice Coefficient relationships using a conventional thresholding approach.