Fig. 2
From: Optogenetic activation of serotonergic neurons changes masticatory movement in freely moving mice
Optogenetic activation of DRN 5-HT neurons during voluntary mastication increases masticatory frequency and decreases EMG bursts. (a) Representative of raw and RMS EMG of masseter muscles during mastication and measured parameters. The masticatory frequency was calculated from the interval between RMS peaks. (b) Pooled data for masticatory frequency after yellow (control) or blue light (activation) application. (c) and (d) Pooled data for RMS peak amplitude (c) and duration (d) in masseter EMG bursts after yellow or blue light application. (e) and (f) Pooled data for RMS peak amplitude (e) and duration (f) in digastric EMG bursts after yellow or blue light application. **P < 0.01, ***P < 0.001 (paired Student’s t test). Comparisons with n.s. have P > 0.05 and are considered not significant. Data are expressed as mean ± SEM. RMS root mean square.
