Fig. 9  | Scientific Reports

Fig. 9 

From: Bioinformatics analysis to design a multi-epitope mRNA vaccine against S. agalactiae exploiting pathogenic proteins

Fig. 9 

Cellular and humoral immune responses using computational simulation against the mRNA vaccine construct as antigen obtained from the C-ImmSim tool (https://kraken.iac.rm.cnr.it/C-IMMSIM/). (A) The antibody generation following antigen administration. (B) The different subsets of the B-cell population (cells per mm3) following three prescriptions. (C) The population of B-cells per state (cells per mm3). (D) The population of helper T-cell (cells per mm3). (E) The population of helper T-cell per state (cells per mm3). (F) The population of cytotoxic T-cell per state (cells per mm3). (G) Population of dendritic cell per state (cells per mm3). (H) Population of macrophage per state (cells per mm3). (I) Cytokines and Interleukins expression with Simpson Index of the immunological response.

Back to article page