Table 1 The main results of MR analysis between COVID 19 traits and migraine.
From: Brain structures as potential mediators of the causal effect of COVID 19 on migraine risk
Exposure | Outcome | nSNPs | OR (95% CI) | P value | PFDR | Power | GSMR | |
|---|---|---|---|---|---|---|---|---|
bxy_pval | OR (95% CI) | |||||||
COVID 19 infection | Migraine | 34 | 1.2502 (1.0592, 1.4756) | 0.0083 | 0.0249 | 0.93 | 0.0103 | 1.25 (1.05, 1.47) |
MA | 27 | 1.4956 (1.1087, 2.0175) | 0.0084 | 0.0168 | 0.98 | 0.0115 | 1.49 (1.09, 2.03) | |
COVID 19 hospitalization | Migraine | 74 | 1.0689 (1.0136, 1.1271) | 0.0138 | 0.0166 | 0.83 | 0.0143 | 1.06 (1.01, 1.12) |
MA | 73 | 1.0919 (1.0134, 1.1764) | 0.0208 | 0.0208 | 0.73 | 0.0205 | 1.09 (1.01, 1.18) | |
COVID 19 severity | Migraine | 46 | 1.0644 (1.0171, 1.1139) | 0.0072 | 0.0432 | 0.88 | 0.0074 | 1.06 (1.02, 1.11) |
MA | 56 | 1.0844 (1.0197, 1.1533 | 0.0098 | 0.0147 | 0.87 | 0.0075 | 1.08 (1.02, 1.14) | |
migraine | COVID 19 infection | 29 | 1.0056 (0.9733, 1.0391) | 0.7359 | 1.1039 | 0.07 | 0.7444 | 1.01 (0.97, 1.04) |
COVID 19 hospitalization | 29 | 0.9946 (0.9242, 1.0703) | 0.8851 | 0.8851 | 0.05 | 0.8645 | 0.99 (0.93, 1.07) | |
COVID 19 severity | 30 | 0.9869 (0.8815, 1.1048) | 0.8183 | 0.9819 | 0.06 | 0.8185 | 0.99 (0.89, 1.10) | |
MA | COVID 19 infection | 10 | 0.9866 (0.9397, 1.0358) | 0.5858 | 1.1716 | 0.13 | 0.5353 | 0.99 (0.95, 1.03) |
COVID 19 hospitalization | 10 | 1.0469 (0.9553, 1.1473) | 0.3266 | 0.9798 | 0.32 | 0.3617 | 1.04 (0.95, 1.14) | |
COVID 19 severity | 5 | 1.1862 (0.9769, 1.4403) | 0.0846 | 0.5076 | 0.73 | 0.1027 | 1.18 (0.97, 1.44) | |
